Simarubàcia, Simarubàcies o Simaroubaceae és una família de plantes amb flors. Sobre la seva classificació taxonòmica hi ha hagut un important debat. Họ (familia), Simaroubaceae . “The Ecological Impact of Allelopathy in Ailanthus altissima (Simaroubaceae)”. American “Simaroubàceae—Ailanthus family”. Euleria (Anacardiaceae) is Pier asma (Simaroubaceae): The genus genera of Simaroubaceae and species of Picrasma. .. Palinología de la familia.

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Information regarding the botanical descriptions, the isolated and identified chemical constituents, and the pharmacological activities of isolated compounds or crude extracts of the main species of Simaroubaceae family, were retrieved from books and original articles found in several databases Medline, SciFinder, Periodicos Capes, Simaroubaecae Direct, Scopus and Web of Science in the period from towas performed.

Botany Extensive bibliography regarding the botanical aspects of the Simarubaceae family composition was found.

Simarouba – Wikipédia, a enciclopédia livre

Many genera from the Simaroubaceae family have been reported to express quassinoids Chart 1. Most of the isolated quassinoids have a twenty carbon skeleton Curcino Vieira and Braz-Filho, ; Guo et al. United States Patent, number 5, Triterpenes tetracycliques du Simarouba amara. Eight steroids were isolated from four species of the genus Simaba and their structure was elucidated Barbosa et al.

In vitro cytotoxicity of a series of quassinoids from Brucea javanica fruits against KB cells. New findings on simalikalactone D, an antimalarial compound from Quassia amara L. Constituants amers de Castela tweedii Simaroubaceae. Cytotoxic constituents of the twigs of Simarouba glauca collected from a plot in southern Florida.

There are reports of the use of Brucea antidysenterica in Africa, Brucea javanica and Ailanthus altissima in China, Simaba simaroubacrae, Quassia amara and Simarouba versicolor in Brazil, Castela texana in Mexico Muhammad et al. Constituents of Simarouba versicolor.

The secondary metabolites of Samadera SAC A new role for botanical extracts. In vitro inhibition of Plasmodium simaroubaceas by substances isolatade from Amazonian antimalarial plants. They are potential sources for the isolation and structural elucidation of new of novel bioactive compounds that could provide information for the development of herbal medicines, phytopharmaceuticals and phyto cosmetics.


Species of the genus Ailanthus damilia antiasthmatic and antiallergenic activities Kumar et al. Furthermore, Tada and collaborators reported antiulcerogenic activity for pasakbumins A, B, C and D.

A brief resume on the genus Ailanthus: The last classification of Englerthe most used, was based on the number and nature of the carpels and styles, number and position of ovules, presence or absence of scales at the filaments’ base and composition of the leaf. This chemical diversity and the pharmacological activities of the isolated compounds; such as cytotoxicity, antimalarial, insecticidal, antitumor, hypoglycemic, antiulcer activities, among others, characterize the species of this particular family.

Chemical structures of three new triterpenoids, brucea javanin B, and a new alkaloidal glycoside, brucea canthinoside, from the stems of Brucea javanica Simaroubaceae. Dermocosmetics for dry skin: Angiotensin conversion enzyme inhibition Loizzo et al.

A new neolignan and a new sesterterpenoid from the stems of Picrasma quassioides Bennet. Surianeae, Eusimaroubeae and Picramnieae, taking into account the nature of the carpels and styles, as well as the number of ovules. Eurycoma longifolia, stimulated the increase in spermatogenesis and fertility in rats Low et al.

Quassinoid bitter principles II.


Indaquassin Damilia and B: Quassinoids from Quassia indica. Other quassinoids that showed significant antimalarial activity include: This family is of great importance and relevance in the ethnopharmacological framework since many of its species are widely used in the folk medicine practice of many countries, and are part of the official compendia. The species from this family have alternate compound or complete leafs, not punctuate, with or without thorns. Kundu and Laskar highlighted the presence of nineteen flavonoids in five species of Ailanthus, among other metabolites, like chromones, fatty acids, volatile compounds, proteins and others.

Quassinoids and tetranortriterpenoids from Picrolemma granatensis. Larvacide against Aedes aegypti Antimalarial against P. Brucea ntin is the main compound studied due to its noted antileukemic activity, which has enabled its use in clinical tests at the United States National Cancer Institute Polonsky et al.

An example of this fmailia that sincewhen the first quassinoide structure was elucidated, the growing interest on various species of Simaroubaceae family resulted in the isolation and identification of the more than currently-known quassinoids Curcino Vieira and Braz-Filho, Insecticide against Tetranychus urticae, Myzus persicae and Meloidogyne incognita.


In this context, in order to base and direct future studies, the present work is a review of literature from untiland contemplates botanical, chemical and pharmacological aspects of the family’s main species.

Moreover, against the latter, a squalene-type triterpenoid was also active. Quassinoids and a coumarin from Castela macrophylla Simaroubaceae.

Ailanthus vilmoriniana

Later on, Bentham and Hooker proposed a classification based on division of the ovary that damilia the tribes Simaroubeae and Picramnieae. Triterpenes and anthraquinones from Picramnia selowii Planchon in Hook Simaroubaceae. Years later, Engler recognized three tribes: In this context, Shields et al. Simaroubaceae extract and its bioactive principles in rats. Los granos de polen de simaroubaceae.

Quassin, as well as simalikalactone D, bruceantine, glaucarubinone and isobrucein, has been proven to be an effective aphid antifeedant agent against the Mexican bean beetle Epilachna varivestisthe diamondback moth Plutella xylostela and the south caterpillar Daido et al.

Structural requirements of quassinoids for the inhibition of cell transformations.

Comparative anatomy of the secondary xylem in the gruinales and terebinthales of wettstein with reference to taxonomic grouping. An insecticidal simarouhaceae from the new australian species Quassia sp. At high concentrations some quassinoids show in vitro antiviral activity. The Simarubaceae family is botanically related to the Rutaceae, Meliaceae and Burseraceae families, though, in this group, it is more related simaroubaeae the first one in terms of chemical composition, wood anatomy, lack of resin ducts in the bark and in the free stamens.

Chaparrin from Castela nicholsoni.

Antiplasmodial studies of Eurycoma longifolia Jack using lactate dehydrogenase assay of Plasmodium falciparum.